KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
9.7
Human Site:
S330
Identified Species:
21.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S330
G
K
L
I
I
K
K
S
K
D
G
S
E
D
K
Chimpanzee
Pan troglodytes
XP_526066
929
104074
V98
Q
K
F
L
N
K
L
V
I
L
V
E
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
R350
L
V
L
L
R
R
Q
R
D
S
Q
E
D
W
T
Dog
Lupus familis
XP_542327
1264
138869
R356
L
V
L
L
R
R
Q
R
D
S
Q
E
D
W
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S333
G
K
L
I
V
K
K
S
K
D
G
S
E
D
K
Rat
Rattus norvegicus
P97573
1190
133575
S332
G
K
L
I
I
K
K
S
R
D
G
S
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
N188
K
A
I
Q
D
Y
L
N
T
H
V
T
A
D
F
Chicken
Gallus gallus
XP_422567
1182
133482
A329
G
K
L
I
I
K
R
A
K
D
G
P
E
D
K
Frog
Xenopus laevis
Q6P4S2
1019
115278
S188
Y
F
S
L
H
I
V
S
D
C
D
M
V
R
T
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
A336
V
M
K
K
M
K
D
A
Q
E
D
W
N
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
I329
G
H
L
V
V
A
K
I
T
G
K
E
M
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
20
6.6
6.6
N.A.
93.3
93.3
N.A.
6.6
80
6.6
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
33.3
33.3
33.3
N.A.
100
100
N.A.
26.6
93.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
19
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
28
37
19
0
19
46
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
37
37
10
10
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
19
% F
% Gly:
46
0
0
0
0
0
0
0
0
10
37
0
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
37
28
10
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
46
10
10
0
55
37
0
28
0
10
0
0
0
46
% K
% Leu:
19
0
64
37
0
0
19
0
0
10
0
0
0
0
0
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
10
0
0
19
0
10
0
19
0
0
0
0
% Q
% Arg:
0
0
0
0
19
19
10
19
10
0
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
0
37
0
19
0
28
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
19
0
0
10
10
10
28
% T
% Val:
10
19
0
10
19
0
10
10
0
0
19
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
19
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _